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Asymptomatic Hypoparathyroidism in Thalassemia Patients Is Not Uncommon, Researchers Find

Screening for asymptomatic hypoparathyroidism should be considered in transfusion-dependent thalassemia patients to allow for early disease detection and intervention, researchers suggest. Their study, “Under-recognized Hypoparathyroidism in Thalassemia,” was published in the Journal of Clinical Research in Pediatric Endocrinology. The occurrence of asymptomatic hypoparathyroidism, defined as low levels…

Specific Transplant Surgery Prevents Hypoparathyroidism in Cancer Patients Needing Thyroidectomy, Study Finds

Transplant surgery that moves two or more parathyroid glands and places them elsewhere in a patient — a process called autotransplantation — can prevent postoperative hypoparathyroidism after the thyroid is totally removed in people with cancer in that gland, researchers report. Their study, “Postoperative hypoparathyroidism after total thyroidectomy for thyroid cance…

Mirror-image Peptides May Lead to Longer-Lasting Therapies, Study Finds

Mirror-image versions of existing, naturally-occurring molecules called peptides, can lead to longer-lasting therapeutics, new research shows. For patients, including those with hypoparathyroidism, the discovery could translate into less frequent injections and possibly more therapies being  developed in a pill form. The study with those findings, “Method to generate highly…

Phase 1 Data Promising for TransCon PTH to Potentially Treat Hypoparathyroidism

TransCon PTH, an investigational therapy for hypoparathyroidism (HP) being developed by Ascendis Pharma, showed positive results in healthy volunteers, according to initial data from a Phase 1 clinical trial. The company presented the trial data recently at the 36th Annual J.P. Morgan Healthcare Conference in San Francisco, California. “We look forward to…