Joana Carvalho, PhD, managing science editor —

The probability a patient has of developing hypoparathyroidism and other complications after undergoing thyroid surgery tends to decrease if the procedure is performed by a surgeon who undertakes a high number of surgeries every year, a study has found. Results from the study, “Association Between Annual Surgeon Total Thyroidectomy…

TransCon PTH normalizes blood levels of calcium and phosphate, and reduces the amount of calcium released in the urine in different animal models, a study shows. These preclinical results support the therapy’s use by people with hypoparathyroidism, the researchers say. The results, “Design and Preclinical Development of…

Approximately 15% of patients undergoing surgery to remove the thyroid gland, called a thyroidectomy, develop permanent hypoparathyroidism, an analysis shows. The extent and timing of the surgery, the expertise of the surgeon who performs the procedure, and the levels of calcium in the patient’s blood immediately after surgery are…

The annual rate of surgeries should increase to reduce patients’ risk of developing hypoparathyroidism after undergoing thyroid surgery, a study says. The study, “Effect of surgeons’ annual operative volume on the risk of permanent Hypoparathyroidism, recurrent laryngeal nerve palsy and Haematoma following thyroidectomy: analysis of United Kingdom registry…

Ascendis Pharma is planning the design of its upcoming Phase 2 clinical trial intended to assess the efficacy and safety of its proprietary, investigational TransCon PTH therapy in adults with hypoparathyroidism. The latest data from the TransCon PTH clinical program was…

Long-term use of recombinant human parathyroid hormone, or rhPTH(1-84), improves mineral balance and normalizes the levels of calcium in the urine of people with chronic hypoparathyroidism, a Phase 3 trial shows. The latest trial findings were discussed at the 28th Annual Scientific & Clinical Conference of the…

A team of Chinese researchers is conducting a clinical trial to test a new parathyroid auto-transplantation site for patients with hypoparathyroidism. The study protocol was published in an article, “Parathyroid autotransplantation at a novel site for better evaluation of the grafted gland function: study protocol for a prospective, randomized…

Postmenopausal women with post-surgical hypoparathyroidism treated with thyroid suppressors are less likely to experience bone loss compared to postmenopausal women with a normal parathyroid function, a study has found. The study, “Trabecular bone score and bone mineral density in patients with postsurgical hypoparathyroidism after total thyroidectomy for differentiated thyroid carcinoma,”…

People with chronic hypoparathyroidism are at higher risk of developing other illnesses — including heart disease, stroke, infections, and epilepsy — than the general population, especially those whose disease did not result from neck surgery,  a study finds. The study, “Increased Mortality and Morbidity in Patients with Chronic Hypoparathyroidism: A population…

Advanced age does not increase the risk of postoperative complications in patients older than 70 who undergo a total thyroidectomy — a surgical procedure that removes the entire thyroid gland — a prospective study shows. The study, “Advanced age does not increase morbidity after total thyroidectomy. Result of…