Joana Carvalho, PhD, managing science editor —

The presence of persistent hypoparathyroidism should prompt physicians to consider a possible diagnosis of autoimmune polyglandular syndrome type 1 (APS-1), a rare genetic disorder, even in the absence of other typical symptoms, according to a case report. The study, “Hypoparathyroidism as the single major component for decades…

Ascendis Pharma anticipates it will announce top-line data from a new Phase 3 clinical trial of TransCon PTH, the company’s investigational hormone replacement therapy for hypoparathyroidism, before the end of the year, according to a recent company update. The study, called PaTHway (NCT04701203), seeks to assess the…

The specific surgical procedures used when patients undergo thyroid surgery —  known as thyroidectomy — dictate the risks they have of developing hypoparathyroidism and other complications, a study found. Because this type of surgery is associated with a high risk of complications and requires specialized care, it should…

People with hypoparathyroidism who wish to undergo weight-loss surgery should consider possible difficulties in maintaining calcium levels within a normal range before undergoing the procedure. The case report with that finding, “The challenges of post-bariatric surgery hypocalcaemia in pre-existing hypoparathyroidism,” was published in the journal…

People with hypoparathyroidism living in the U.S. still struggle to receive proper medical care, particularly during emergency room visits, according to findings of a survey conducted by the HypoPARAthyroidism Association (HPA). The results of the HPA’s “Voices of Hypopara” survey were released in support of World Hypoparathyroidism…

Patients with DiGeorge syndrome tend to experience hypoparathyroidism symptoms earlier — and ones that are milder — compared to those with idiopathic hypoparathyroidism, a study has found. The study, “Clinical and Genetic Findings in a Chinese Cohort of Patients With DiGeorge Syndrome-Related Hypoparathyroidism,” was published in…

Careful identification and dissection of the parathyroid glands during thyroid surgery can reduce the risk of hypoparathyroidism after the procedure, a study suggests. The study, “Risk Factors of Incidental Parathyroidecomy in Thyroid Surgery,” was published in the journal Cureus. Hypoparathyroidism is…

The pharmacological properties of hPTH(1-34) allow the oral medication to be administered at different dosing regimens to suit the individual needs of patients with hypoparathyroidism, according to data from a Phase 2 study. The findings were presented in the poster “An Evaluation of the Pharmacodynamic Effects of…

Researchers may have found a way to decrease the risks of temporary or permanent hypoparathyroidism following thyroid surgery. It consists of a surgical technique to preserve blood supply to the parathyroid glands and an injection of small carbon particles that allow surgeons to spot the parathyroid…

Takeda has issued a U.S. recall of its prescription parathyroid hormone Natpara, due to the potential risk of small rubber fragments detaching from the products’ external protection cap with repeated use. The recall includes all doses of Natpara (human parathyroid hormone, or PTH) for injection — 25 mcg,…