Author Archives: Alice Melao

Hypoparathyroidism can trigger serious changes in heartbeat rhythm as a consequence of reduced blood levels of calcium, a case report highlights. The case was described in the study “Ventricular Arrhythmia Precipitated by Severe Hypocalcaemia Secondary to Primary Hypoparathyroidism,” which was published in the journal Case Reports…

Chronic hypoparathyroidism is linked to long-term renal and cardiovascular complications, and can have severe implications on patients’ health-related quality of life, according to data from several studies. The data, presented by Takeda Pharmaceutical during the Endocrine Society’s 2019 Annual Meeting (ENDO) in New Orleans, also included the final outcomes regarding…

Treatment with an immunotherapy regimen against skin cancer resulted in a rare case of immune-mediated hypoparathyroidism, according to a case report. This rare case was described in a study, “Inflammation-induced hypoparathyroidism triggered by combination immune checkpoint blockade for melanoma,” published in the Journal for ImmunoTherapy of Cancer.

Ascendis Pharma is planning to initiate clinical studies to evaluate the potential of its investigational therapy TransCon PTH in adult patients with hypoparathyroidism. The company has submitted an investigational new drug (IND) application with the U.S. Food and Drug Administration (FDA) to start the PaTH Forward Phase 2…

Entera Bio’s investigational parathyroid hormone compound called Oral PTH (1-34) appears to be able to increase calcium levels in patients with hypoparathyroidism, interim results from a Phase 2 trial show. It can also increase blood levels of active vitamin D and reduce phosphate levels — two other hallmarks…

Hypoparathyroidism may lead to the development of a rare neurological disorder manifesting with seizures, a case study reveals. The study, “A Case of Seizure Revealing Fahr’s Syndrome with Primary Hypoparathyroidism,” was published in the American Journal of Case Reports. The patient, a 52-year-old man, was admitted…

Emergency cards can help ease the diagnosis and treatment of an acute crisis of low or high blood calcium levels among patients with…