Alice Melao,  —

Articles by Alice Melao

Chronic Hypoparathyroidism Linked to Long-term Renal, Cardiovascular Problems, Studies Show

Chronic hypoparathyroidism is linked to long-term renal and cardiovascular complications, and can have severe implications on patients’ health-related quality of life, according to data from several studies. The data, presented by Takeda Pharmaceutical during the Endocrine Society’s 2019 Annual Meeting (ENDO) in New Orleans, also included the final outcomes regarding…

Report Describes How Skin Cancer Treatment Resulted in Hypoparathyroidism

Treatment with an immunotherapy regimen against skin cancer resulted in a rare case of immune-mediated hypoparathyroidism, according to a case report. This rare case was described in a study, “Inflammation-induced hypoparathyroidism triggered by combination immune checkpoint blockade for melanoma,” published in the Journal for ImmunoTherapy of Cancer.

Ascendis Pharma Seeks FDA Approval for TransCon PTH Phase 2 Trial

Ascendis Pharma is planning to initiate clinical studies to evaluate the potential of its investigational therapy TransCon PTH in adult patients with hypoparathyroidism. The company has submitted an investigational new drug (IND) application with the U.S. Food and Drug Administration (FDA) to start the PaTH Forward Phase 2…