The risk of fractures in the vertebrae, the bones in the spine, was 55% higher in people with chronic hypoparathyroidism than in the general population, a nationwide study in Sweden found. Conversely, the risk of femur (thighbone) fractures was 30% less common in the hypoparathyroidism group. Chronic hypoparathyroidism patients…
Hypoparathyroidism is often temporary in children who undergo surgical removal of the thyroid, or thyroidectomy, with most recovering normal parathyroid function within six months, a study in China shows. The time needed to recover from hypoparathyroidism was found to be closely related to the levels of parathyroid hormone (PTH)…
Yorvipath (palopegteriparatide) has been approved in Australia as a parathyroid hormone (PTH) replacement therapy for adults with chronic hypoparathyroidism. The news follows similar approvals in the European Union in 2023, and in the U.S. last year. Yorvipath will be made available in Australia through Specialised Therapeutics, under…
Slightly less than 20% of people who had their thyroid gland removed had hypoparathyroidism a year after the surgery, according to a 20-year study in Denmark. An increase in mortality risk was only found when the the surgery was due to cancer, but mortality was unaffected in benign cases.
People with hypoparathyroidism experience worse quality of life, with women showing a higher burden of disease than men, according to a recent survey in Germany. In addition, patients who’ve had the disease longer report a lower burden of their symptoms. “Investigations on potential coping strategies might give an explanation…
People with autoimmune hypoparathyroidism who have anti-CaSR antibodies — which play a role in regulating the parathyroid hormone, known as PTH — may benefit from adding steroid therapy to standard vitamin D and calcium supplementation, a case report suggests. That report described a 55-year-old woman who’d had seizures for 35…
Two severe cases of hypoparathyroidism were associated with two newly identified mutations in the glial cell missing homolog 2 (GCM2) gene by scientists in India. “This report demonstrates the critical role of GCM2 activity in human parathyroid gland development through clinical and genetic analysis of 2 patients with hypoparathyroidism,” the…
Treatment with radioiodine extended the recovery of parathyroid function in patients who underwent surgical thyroid removal, in some cases beyond one year, a study in China has found. Although some studies suggest that hypoparathyroidism might be permanent if it lasts more than six months, this diagnosis “should be cautiously made…
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