News

Study highlights kidney function loss risk in hypoparathyroidism

People with long-lasting hypoparathyroidism after thyroid surgery are at risk of having deteriorating kidney function, according to a study from Spain. “This study demonstrated that patients were at greater risk of chronic kidney disease, progression to end-stage kidney disease, and faster decline in [kidney function] compared to subjects without…

Hypoparathyroidism in children often temporary after surgery

Hypoparathyroidism is often temporary in children who undergo surgical removal of the thyroid, or thyroidectomy, with most recovering normal parathyroid function within six months, a study in China shows. The time needed to recover from hypoparathyroidism was found to be closely related to the levels of parathyroid hormone (PTH)…

Hypoparathyroidism treatment MBX 2109 trial enrolled

A Phase 2 clinical trial testing MBX 2109 in people with chronic hypoparathyroidism has finished enrolling participants, according to MBX Biosciences, the treatment’s developer and sponsor of the trial. “Completion of enrollment in our Phase 2 trial in [hypoparathyroidism] marks a significant milestone for MBX and brings us closer…

Yorvipath approved in Australia for chronic hypoparathyroidism

Yorvipath (palopegteriparatide) has been approved in Australia as a parathyroid hormone (PTH) replacement therapy for adults with chronic hypoparathyroidism. The news follows similar approvals in the European Union in 2023, and in the U.S. last year. Yorvipath will be made available in Australia through Specialised Therapeutics, under…

Reactive supplement use works in postoperative hypoparathyroidism

Note: This story was updated Dec. 16, 2024, to correct errors in terminology from hyperparathyroidism to hypoparathyroidism. Reactive supplement use — giving oral supplements of calcium and vitamin D after total thyroidectomy, or the complete surgical removal of the thyroid gland — is safe and effective in patients experiencing…

Corticosteroids low in post-surgical hypoparathyroidism patients

People with hypoparathyroidism due to surgery have reduced levels of corticosteroids, or hormones produced by the adrenal gland, despite adequate treatment with calcium and vitamin D supplementation, a small study reported. Data showed that short-term replacement parathyroid hormone (PTH) therapy partly restored these hormones to normal levels. Low hormone…