Author Archives: Marta Figueiredo PhD

FDA Rejects Changes to Natpara Cartridge, Delaying Its Relaunch

The U.S. Food and Drug Administration (FDA) has rejected Takeda Pharmaceutical’s proposed changes to address the risk of rubber fragments detaching into Natpara’s cartridge that led to the therapy’s U.S. recall in 2019. This treatment for hypoparathyroidism involves puncturing the medication’s cartridge rubber septum — a disk…

APS1 Case Report Supports Early Immunosuppressive Treatment

Starting immunosuppressive treatment early in the disease course normalized some signs of autoimmunity, halted the development of additional autoimmune diseases, and reversed total body hair loss in a girl with autoimmune polyglandular syndrome type 1 (APS1), a case study shows. While immunosuppressive therapies have been generally reserved for life-threatening…

Calcium Deposits in Kidneys Common in Hypoparathyroidism

Calcium deposits — known as calcifications — in the kidneys and higher-than-normal levels of calcium in urine are common in people with chronic hypoparathyroidism, according to a small Danish study. Notably, the presence of these calcifications was neither significantly associated with the levels of calcium in the urine or…

Hypoparathyroidism After Thyroid Surgery Can Greatly Affect Life Quality

People who develop chronic hypoparathyroidism following surgery to remove the thyroid gland have significantly poorer quality of life than those whose surgery does not permanently damage the neighboring parathyroid glands, a Danish study shows. Notably, hypoparathyroidism’s negative affect on life was independent of the drop in thyroid-related hormones (hypothyroidism) due…